Saffron is the most expensive spice in the world! It is produced from the saffron crocus flower (Crocus sativus). Saffron spice is actually the dried stigmas, which are the insides of a flower that catch the pollen. It has a deep auburn colour and sweet flavour.

Crocus Flower Habitat

The Crocus flower is native to Southwest Asia and some areas of Europe. Though it is often harvested to be used as a spice for cooking or for flavoring tea, it is also known to have many health benefits as a herbal supplement.

Harvesting Saffron

The stigmas can only be picked from the flowers by hand as machines are not delicate enough. It takes 250,000 stigmas to make just half a kilo of saffron, hence its high price, however you only need a pinch as it is very strong.

Saffron Health Benefits

Saffron has lost some of its popularity as a spice due to more common and affordable herbs and spices, yet it still remains as a herbal supplement because of its many medicinal benefits. The amount of ailments Saffron can be used to treat is extensive.

Below is a list of some of the more common ailments that a herbal saffron supplement can help with:

Saffron for Depression

Saffron, when taken correctly, is effective at treating mild to moderate depression. It has been proven to be just as effective as popular prescription medications.

Whilst research is ongoing, several mechanisms have been proposed to explain how saffron may help alleviate depressive symptoms:

Serotonin Modulation: Saffron contains bioactive compounds such as crocin, crocetin, and safranal, which may influence neurotransmitter levels in the brain. Some studies suggest that saffron may increase the availability of serotonin, a neurotransmitter associated with mood regulation. By enhancing serotonin levels, saffron may help improve mood and reduce symptoms of depression.

Neuroprotection: Saffron exhibits antioxidant and neuroprotective properties, which may help protect brain cells from oxidative stress and inflammation. Oxidative stress and inflammation have been implicated in the pathophysiology of depression, and saffron’s antioxidant activity may help mitigate these processes, thereby reducing depressive symptoms.

Endorphin Release: Saffron has been shown to increase the release of endorphins, which are natural compounds in the brain that promote feelings of well-being and reduce pain perception. By stimulating endorphin release, saffron may exert mood-lifting effects and enhance emotional resilience, potentially alleviating symptoms of depression.

Anti-inflammatory Effects: Chronic inflammation has been linked to depression, and saffron exhibits anti-inflammatory properties that may help modulate the inflammatory response in the body and brain. By reducing inflammation, saffron may contribute to improved mood and overall mental health.

Hormonal Regulation: Saffron contains compounds that may influence hormone levels in the body, including cortisol, the stress hormone. High levels of cortisol have been associated with depression and anxiety, and saffron’s potential to modulate cortisol levels may help alleviate depressive symptoms and promote relaxation.

Antidepressant Activity: Several clinical studies have investigated the antidepressant effects of saffron and have reported promising results. Saffron extracts and supplements have been shown to be effective in reducing symptoms of depression, including sadness, anxiety, and insomnia, in individuals with mild to moderate depression.

It’s important to note that while saffron shows promise as a natural remedy for depression, more research is needed to fully understand its mechanisms of action and efficacy. Additionally, saffron supplements should not be used as a replacement for conventional treatments for depression, such as psychotherapy or medication. If you are experiencing symptoms of depression, it’s essential to seek guidance from a healthcare professional for an accurate diagnosis and appropriate treatment plan. They can help you explore safe and effective strategies for managing depression and improving overall mental well-being.

Saffron for Asthma

Asthma can be a frightening problem for a lot of people. It can make it very difficult to breathe because your lungs become inflamed, meaning your airways begin to restrict which causes less air to be able to pass through.

Saffron has been studied for its potential therapeutic effects in various respiratory conditions, including asthma. Some animal studies suggest that saffron might have bronchodilator effects, meaning it could potentially help widen the airways and ease breathing. Saffron may also help to clear the airways which further helps to ease breathing.

While research on saffron’s effects on asthma is limited, several mechanisms have been proposed to explain its potential benefits:

Anti-inflammatory Properties: Chronic inflammation plays a significant role in the pathogenesis of asthma, contributing to airway inflammation, bronchoconstriction, and respiratory symptoms. Saffron contains bioactive compounds such as crocin, crocetin, and safranal, which exhibit anti-inflammatory properties. These compounds may help suppress pro-inflammatory cytokines, inhibit inflammatory signaling pathways, and modulate immune responses in the airways. By reducing inflammation, saffron may help alleviate airway inflammation and improve asthma symptoms.

Bronchodilator Effects: Saffron has been reported to exhibit bronchodilator effects, meaning it may help relax and widen the airways, making it easier to breathe. Some studies suggest that saffron may enhance airway smooth muscle relaxation and inhibit bronchoconstriction, potentially improving airflow and respiratory function in individuals with asthma. By promoting bronchodilation, saffron may help alleviate symptoms such as wheezing, coughing, and shortness of breath associated with asthma.

Antioxidant Activity: Oxidative stress is implicated in the pathogenesis of asthma, contributing to airway inflammation, oxidative damage to lung tissues, and exacerbation of respiratory symptoms. Saffron exhibits potent antioxidant properties due to its high content of carotenoids and other bioactive compounds. These antioxidants may help neutralize free radicals, reduce oxidative damage to airway tissues, and mitigate inflammation in the lungs. By scavenging free radicals and reducing oxidative stress, saffron may help protect against asthma-related inflammation and respiratory complications.

Immunomodulatory Effects: Saffron may modulate immune responses in the respiratory system, potentially influencing the pathogenesis of asthma. Some studies suggest that saffron may regulate immune cell activity, cytokine production, and allergic responses in the airways. By modulating immune function, saffron may help prevent or mitigate allergic inflammation and immune-mediated reactions that contribute to asthma exacerbations.

Mucolytic Effects: Saffron has been reported to exhibit mucolytic properties, meaning it may help break down and thin mucus secretions in the airways. This can facilitate the clearance of mucus from the lungs, reduce airway obstruction, and improve respiratory function in individuals with asthma. By promoting mucus clearance, saffron may help alleviate coughing, chest congestion, and respiratory distress associated with asthma exacerbations.

While preliminary evidence suggests that saffron may offer potential benefits for asthma management, more research is needed to fully elucidate its mechanisms of action and efficacy in this regard. Additionally, saffron supplementation should not replace standard asthma treatments such as bronchodilators, corticosteroids or other controller medications prescribed by healthcare professionals.

If you have asthma or respiratory symptoms, it’s essential to consult with a healthcare provider for proper diagnosis, treatment and management of your condition. They can help develop a personalized asthma management plan that may include lifestyle modifications, medication management and complementary therapies such as saffron supplementation, if appropriate.

Saffron for Sleep Issues

If you are having trouble sleeping, using a saffron herbal supplement can also help you to avoid those restless or sleepless nights. The best way to use saffron to help you sleep is by mixing it with some milk or tea and your favorite sweetener and then drinking it before bed.

The Research – Saffron has been traditionally used for its potential calming and sedative effects, and some studies suggest that it may help improve sleep quality and duration. While more research is needed to fully understand the mechanisms involved, several factors may contribute to saffron’s potential benefits for sleep, which we will explore below:

Serotonin Modulation: Saffron contains bioactive compounds that may influence neurotransmitter levels in the brain, including serotonin, a neurotransmitter involved in regulating mood and sleep-wake cycles. By modulating serotonin levels, saffron may help promote relaxation and facilitate the onset of sleep.

GABAergic Activity: Saffron has been shown to increase the activity of gamma-aminobutyric acid (GABA), a neurotransmitter with calming and sedative effects. GABA helps inhibit neuronal excitability and promotes feelings of relaxation and tranquility, which are essential for initiating and maintaining sleep.

Endorphin Release: Saffron has been reported to stimulate the release of endorphins, which are natural compounds in the brain that promote feelings of well-being and reduce pain perception. Endorphins have been implicated in sleep regulation, and their release may contribute to saffron’s potential sleep-promoting effects.

Anti-anxiety Effects: Saffron exhibits anxiolytic (anti-anxiety) properties and may help reduce feelings of stress and anxiety that can interfere with sleep. By promoting relaxation and reducing psychological arousal, saffron may facilitate the transition from wakefulness to sleep.

Antioxidant and Anti-inflammatory Effects: Chronic inflammation and oxidative stress have been linked to sleep disturbances, and saffron’s antioxidant and anti-inflammatory properties may help mitigate these processes. By reducing inflammation and oxidative damage in the brain and body, saffron may promote a conducive environment for restful sleep.

Regulation of Circadian Rhythms: Saffron may influence circadian rhythms, the internal biological clock that regulates the sleep-wake cycle. Some studies suggest that saffron may help synchronize circadian rhythms and promote a more regular sleep pattern.

Reduction of Sleep Disturbances: Saffron has been reported to alleviate symptoms of sleep disturbances such as insomnia, nightmares, and sleep fragmentation. By addressing underlying factors contributing to poor sleep quality, saffron may help improve overall sleep duration and continuity.

It’s important to note that while saffron shows promise as a natural sleep aid, more research is needed to fully understand its mechanisms of action and efficacy for sleep improvement. Additionally, individual responses to saffron may vary, and it may not be effective for everyone.

If you are experiencing persistent sleep difficulties, it’s advisable to seek guidance from a healthcare professional for a comprehensive evaluation and appropriate treatment recommendations. They can help identify underlying factors contributing to sleep disturbances and develop a tailored approach to improve sleep quality and overall well-being.

Saffron for Arteriosclerosis

Arteriosclerosis is a very dangerous condition in which the arteries begin to harden and narrow due to a build up of plaque. When your arteries harden they have trouble transporting the amount of oxygen needed to different parts of the body. Because this condition is not easy to detect in early stages, it is vital to take precautions early on.

This is where using saffron as a herbal supplement can help to decrease the chances of getting arteriosclerosis. Saffron has been studied for its potential cardiovascular benefits, including its effects on arteriosclerosis. Saffron acts as a stimulant and an antioxidant to help increase blood circulation throughout the body.

While research is ongoing, several mechanisms have been proposed to explain how saffron may help mitigate arteriosclerosis:

Antioxidant Activity: Saffron contains bioactive compounds such as crocin, crocetin, and safranal, which possess potent antioxidant properties. Oxidative stress plays a significant role in the development and progression of arteriosclerosis by promoting inflammation, endothelial dysfunction, and lipid peroxidation. Saffron’s antioxidant activity may help neutralize free radicals, reduce oxidative damage to blood vessels, and inhibit the formation of atherosclerotic plaque.

Anti-inflammatory Effects: Chronic inflammation is a key driver of arteriosclerosis, contributing to endothelial dysfunction, foam cell formation, and plaque formation in the arteries. Saffron has been shown to exhibit anti-inflammatory properties by suppressing pro-inflammatory cytokines, inhibiting leukocyte adhesion, and modulating inflammatory signaling pathways. By reducing inflammation, saffron may help attenuate the inflammatory processes underlying arteriosclerosis and promote vascular health.

Lipid Modulation: Dyslipidemia, characterized by elevated levels of LDL cholesterol and triglycerides and decreased levels of HDL cholesterol, is a major risk factor for arteriosclerosis. Saffron supplementation has been reported to improve lipid profiles by lowering LDL cholesterol and triglyceride levels and increasing HDL cholesterol levels. These lipid-modulating effects may help reduce the accumulation of atherosclerotic plaque in the arteries and mitigate the progression of arteriosclerosis.

Endothelial Protection: Endothelial dysfunction, characterized by impaired vasodilation, increased vascular permeability, and pro-thrombotic activity, is an early hallmark of arteriosclerosis. Saffron has been shown to enhance endothelial function by promoting nitric oxide production, improving vascular tone, and reducing oxidative stress and inflammation in endothelial cells. By preserving endothelial integrity and function, saffron may help maintain arterial health and prevent the development of arteriosclerosis.

Anti-thrombotic Activity: Saffron exhibits antiplatelet and anticoagulant properties, which may help prevent thrombus formation and reduce the risk of arterial thrombosis, a common complication of arteriosclerosis. By inhibiting platelet aggregation, promoting fibrinolysis, and modulating coagulation factors, saffron may help maintain blood flow and prevent the occlusion of atherosclerotic arteries.

While preliminary evidence suggests that saffron may offer potential benefits for mitigating arteriosclerosis, more research is needed to fully elucidate its mechanisms of action and efficacy in preventing and treating cardiovascular disease.

It’s important to note that saffron supplementation should not replace conventional therapies for arteriosclerosis, and individuals with cardiovascular risk factors or existing cardiovascular conditions should consult with a healthcare professional before using saffron supplements as part of their treatment regimen.

Additionally, lifestyle modifications such as a heart-healthy diet, regular exercise, smoking cessation, and management of other risk factors remain essential for reducing the risk of arteriosclerosis and promoting cardiovascular health.

Anti-Cancer Effects of Saffron

According to research, saffron can help fight cancer. Cancer cells grow by building and creating their own blood supply in the body. Saffron is thought to enter the cancer cells and send them a signal to commit suicide (known as Apoptosis), thus leading to the cancer dying off. Saffron contains carotenoids which are thought to cause toxic and deadly reactions to certain cancer cells in the body, such as leukemia cells, sarcoma cells and cancerous carcinoma cells.

Saffron has been studied for its potential anticancer properties, although more research is needed to fully understand its mechanisms of action and efficacy in cancer prevention and treatment.

Several mechanisms have been proposed to explain how saffron may exert anticancer effects:

Antioxidant Activity: Saffron contains bioactive compounds such as crocin, crocetin, and safranal, which exhibit potent antioxidant properties. Oxidative stress, resulting from an imbalance between free radicals and antioxidants in the body, can lead to DNA damage, inflammation, and cell proliferation, contributing to cancer development and progression. Saffron’s antioxidant activity may help neutralize free radicals, reduce oxidative damage to cells, and inhibit carcinogenesis.

Anti-inflammatory Effects: Chronic inflammation plays a critical role in the development and progression of cancer by promoting tumor growth, angiogenesis, and metastasis. Saffron has been shown to exhibit anti-inflammatory properties by suppressing pro-inflammatory cytokines, inhibiting inflammatory signaling pathways, and modulating immune responses. By reducing inflammation, saffron may help inhibit tumor growth and metastasis and enhance the body’s ability to fight cancer.

Apoptosis Induction: Saffron has been reported to induce apoptosis, or programmed cell death, in cancer cells. Apoptosis is a natural process that helps eliminate damaged or abnormal cells, including cancer cells, to maintain tissue homeostasis and prevent tumor formation. Saffron’s ability to trigger apoptosis in cancer cells may help inhibit tumor growth and promote cancer cell death, thereby suppressing tumor progression.

Cell Cycle Arrest: Saffron has been shown to disrupt the cell cycle, the process by which cells divide and proliferate, in cancer cells. By inducing cell cycle arrest at specific checkpoints, saffron may inhibit uncontrolled cell growth and proliferation characteristic of cancer cells. By interfering with the cell cycle, saffron may help prevent tumor formation and progression.

Angiogenesis Inhibition: Saffron may inhibit angiogenesis, the process by which new blood vessels form to supply nutrients and oxygen to tumors. Angiogenesis is essential for tumor growth, invasion, and metastasis, and inhibiting angiogenesis can help limit tumor progression. Saffron’s ability to inhibit angiogenesis may help deprive tumors of the blood supply they need to grow and spread.

Chemopreventive Effects: Some studies suggest that saffron may have chemopreventive properties, meaning it may help prevent the initiation, promotion, and progression of cancer. By targeting multiple stages of carcinogenesis, including DNA damage, inflammation, and tumor growth, saffron may help reduce the risk of cancer development in healthy individuals or individuals at high risk for cancer.

While preliminary evidence suggests that saffron may offer potential benefits for cancer prevention and treatment, more research is needed to validate its efficacy and safety in clinical settings. Additionally, saffron supplementation should not replace conventional cancer treatments such as chemotherapy, radiation therapy or surgery. If you or a loved one is diagnosed with cancer, it’s essential to consult with a healthcare professional for personalized treatment recommendations and comprehensive cancer care.

Saffron for Menstrual Relief

Saffron has been traditionally used for its potential benefits in promoting menstrual health and alleviating symptoms associated with menstruation. For women who have irregular periods, saffron can be taken to help regulate their menstruation as well as help relieve pain that is associated with periods. Along with period relief, saffron can also help to reduce chronic uterus bleeding.

While scientific research on saffron’s effects on menstruation is limited, several mechanisms have been proposed to explain its potential benefits:

Uterine Contractions: Saffron has been traditionally used to stimulate uterine contractions and regulate menstrual cycles. Some studies suggest that saffron may possess emmenagogue properties, meaning it may help promote menstruation and relieve menstrual irregularities. By stimulating uterine contractions, saffron may facilitate the shedding of the uterine lining and promote regular menstruation.

Hormonal Modulation: Saffron contains bioactive compounds, including crocin, crocetin, and safranal, which may influence hormone levels in the body. Some research suggests that saffron may help regulate estrogen and progesterone levels, which play crucial roles in menstrual cycle regulation. By modulating hormone levels, saffron may help regulate menstrual cycles and alleviate symptoms of hormonal imbalance, such as irregular periods, amenorrhea (absence of menstruation), or oligomenorrhea (infrequent menstruation).

Pain Relief: Saffron has been reported to possess analgesic (pain-relieving) properties, which may help alleviate menstrual cramps (dysmenorrhea) and other menstrual-related discomfort. Some studies suggest that saffron may inhibit the release of prostaglandins, substances that promote uterine contractions and contribute to menstrual pain. By reducing prostaglandin levels, saffron may help alleviate menstrual cramps and promote comfort during menstruation.

Mood Enhancement: Saffron has been studied for its potential effects on mood and emotional well-being. Some research suggests that saffron may help improve mood, reduce anxiety, and alleviate symptoms of premenstrual syndrome (PMS), such as irritability, mood swings, and emotional instability. By promoting emotional balance and reducing psychological distress, saffron may help improve overall menstrual health and well-being.

Antioxidant and Anti-inflammatory Effects: Saffron exhibits antioxidant and anti-inflammatory properties, which may help mitigate oxidative stress and inflammation associated with menstruation. Oxidative stress and inflammation have been implicated in the pathogenesis of menstrual disorders and symptoms such as dysmenorrhea, menorrhagia (heavy menstrual bleeding), and pelvic pain. By reducing oxidative damage and inflammation, saffron may help alleviate menstrual-related symptoms and promote menstrual health.

It’s important to note that while saffron may offer potential benefits for menstruation, more research is needed to fully elucidate its mechanisms of action and efficacy in this regard. Additionally, individual responses to saffron may vary, and it may not be effective for everyone. If you are experiencing menstrual irregularities or severe menstrual symptoms, it’s essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment recommendations. They can help identify underlying factors contributing to menstrual issues and develop a tailored approach to support menstrual health and well-being.

How To Take Saffron

For it to be effective, the most important thing is to make certain that you are buying 100% real saffron from a reputable dealer. You also need to make sure that the saffron only consists of the red filaments.

When you receive the saffron, it is best to soak it in either broth, milk or warm water before you cook with it. This will help make it more potent when you add it to any recipe.

If you do not want to cook with the saffron, an alternative way to use it is to add it into a tea or some milk to consume. To make it, just mix at least ten strands of the saffron into your drink with some sweetener of your choice. Mix it well and enjoy. When taken at night, it can also help treat depression that is associated with insomnia.

Always take care when taking herbs and Read Our Disclaimer.

Saffron Notes / Side Effects

Saffron, derived from the stigma of the Crocus sativus flower, is a highly prized spice known for its distinct flavor, aroma, and vibrant color. When used in culinary amounts, saffron is generally safe for most people. However, consuming large quantities of saffron or using it medicinally may lead to potential side effects.

Here are some possible side effects of saffron:

Allergic Reactions: Some individuals may be allergic to saffron and experience allergic reactions such as itching, rash, hives, swelling, or difficulty breathing upon exposure to saffron. If you have known allergies to plants in the Iridaceae family or have a history of allergies to spices, you may be at higher risk of allergic reactions to saffron.

Digestive Issues: Ingesting large amounts of saffron may cause gastrointestinal upset, including nausea, vomiting, diarrhea, or stomach discomfort. This is more likely to occur with excessive consumption of saffron or when using saffron supplements in high doses.

Hypotension: Saffron may have hypotensive (blood pressure-lowering) effects, particularly when consumed in large amounts or used medicinally. Individuals with low blood pressure or those taking medications to lower blood pressure should use saffron cautiously and monitor their blood pressure levels closely.

Uterine Stimulation: Saffron has been traditionally used to stimulate uterine contractions and menstruation. Pregnant women should avoid consuming large amounts of saffron, as it may increase the risk of uterine contractions and potentially lead to miscarriage or preterm labor. It’s advisable for pregnant women to use culinary amounts of saffron in food preparation rather than using it medicinally or in concentrated forms.

Interaction with Medications: Saffron may interact with certain medications, including antidepressants, sedatives, and blood thinners. Saffron contains compounds that may affect neurotransmitter levels, serotonin activity, and blood clotting, potentially enhancing or interfering with the effects of these medications. If you are taking medications, especially those with narrow therapeutic windows or that affect serotonin levels or blood clotting, it’s essential to consult with a healthcare professional before using saffron supplements.

Hypersensitivity to Light: In rare cases, excessive consumption of saffron or use of saffron supplements may lead to a condition known as photosensitivity, where individuals become more sensitive to sunlight and may experience skin reactions such as redness, itching, or burning when exposed to sunlight or UV rays.

If you experience any adverse reactions or concerns after using saffron, discontinue use and consult with a healthcare professional for further guidance.